Samphire Neuroscience
Samphire Neuroscience offers medical-grade, neuroscience-based solutions.
Their product, Nettle™, is an award-winning, CE-marked medical device clinically proven to alleviate menstrual cycle symptoms such as low mood, and pain.
Nettle™ operates by delivering gentle, targeted pulses to specific brain regions responsible for mood and pain regulation, providing a non-invasive, drug-free alternative for menstrual symptom management.
Innovation of the Year: MEDICA 2025
Women's Health Innovation of the Year: 2024
Healthcare Innovation World Cup: 1st place in the Innovation World Cup Series
Awards
Samphire Neuroscience's Nettle™ device leverages transcranial Direct Current Stimulation (tDCS) to alleviate menstrual-related symptoms. tDCS is a non-invasive neuromodulation technique that has been studied for over three decades, demonstrating safety and efficacy in various applications. Nettle™ specifically targets two brain regions:
Dorsolateral Prefrontal Cortex (DLPFC): This area is associated with mood regulation. By stimulating the DLPFC, Nettle™ addresses emotional symptoms such as low mood and anxiety commonly experienced during the luteal phase of the menstrual cycle.
Motor Cortex (M1): Involved in pain perception, stimulating the motor cortex with Nettle™ alleviates menstrual pain by modulating pain pathways.
Clinical studies have shown that Nettle™ effectively reduces pain and improves mood and functionality during the menstrual cycle, offering a promising alternative to traditional treatments.
Learn more here.
Research